Long-awaited treatment for hepatitis C virus decompensated cirrhosis
نویسندگان
چکیده
منابع مشابه
Treatment of Hepatitis B in Decompensated Liver Cirrhosis
Chronic hepatitis B infection progresses from an asymptomatic persistently infected state to chronic hepatitis, cirrhosis, decompensated liver disease, and/or hepatocellular carcinoma. About 3% of patients with chronic hepatitis develop cirrhosis yearly, and about 5% of individuals with hepatitis B cirrhosis become decompensated annually. The outcome for patients with decompensated cirrhosis is...
متن کاملSplenectomy prior to antiviral therapy in patients with hepatitis C virus related decompensated cirrhosis.
Patients with hepatitis C virus-related decompensated cirrhosis can benefit from interferon-based antiviral therapy, but the common complication of cytopenia is a contraindication for this treatment. Splenectomy prior to interferon therapy may alleviate this problem. To investigate whether splenectomy improves the efficacy of antiviral therapy, 13 interferon-naïve hepatitis C virus decompensate...
متن کاملTreatment of decompensated cirrhosis secondary to hepatitis C with antiviral therapy.
OBJECTIVE To treat decompensated hepatitis C patient with interferon, ribavirin and amantidine to ascertain the sustained viral response. STUDY DESIGN Descriptive study. PLACE AND DURATION OF STUDY Shifa International Hospital, Islamabad, from January 2007 to January 2012. METHODOLOGY HCV PCR patients with decompensated hepatitis C, who had developed a complication like ascites, encephalo...
متن کاملImmunopathogenesis in hepatitis C virus cirrhosis.
HCV (hepatitis C virus) has a high propensity to persist and to cause chronic hepatitis C, eventually leading to cirrhosis. Since HCV itself is not cytopathic, liver damage in chronic hepatitis C is commonly attributed to immune-mediated mechanisms. HCV proteins interact with several pathways in the host's immune response and disrupt pathogen-associated pattern recognition pathways, interfere w...
متن کاملTreatment of Hepatitis B Virus Cirrhosis
Article type: Editorial Implication for health policy/practice/research/medical education: Untreated Hepatitis B Virus (HBV) cirrhosis runs a progressive course to liver failure and death. However, new antivirals that adequately control HBV replication can interrupt this ominous clinical course, are capable of reverting liver fibrosis and may avoid liver transplantation. Therefore indefinite tr...
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ژورنال
عنوان ژورنال: Journal of Gastroenterology
سال: 2019
ISSN: 0944-1174,1435-5922
DOI: 10.1007/s00535-018-01538-6